Fig. 1 · Structure
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PEG3-methylamine
PROTAC Linkers
PEG3-methylamine is a polyethylene glycol (PEG)-derived linker specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of PROTACs by enhancing solubility and stability while optimizing the binding interactions with target proteins. Its application in drug discovery allows researchers to create innovative therapeutic agents aimed at selective protein degradation, thus offering new strategies for treating various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 282551-10-4 |
| Applications | PROTAC Linkers |
| Formula | C7H17NO3 |
| Molecular Weight | 163.21 |
| SMILES | CNCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.