Fig. 1 · Structure
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Pelacarsen sodium
Apolipoprotein(a) Inhibitor
Pelacarsen sodium is an apolipoprotein(a) inhibitor that functions as a GalNAc3-conjugated 2′-MOE-modified antisense oligonucleotide. By specifically targeting and reducing levels of apolipoprotein(a), Pelacarsen sodium plays a significant role in lipid metabolism and cardiovascular disease research. It is valuable for studies aimed at exploring new therapies for atherosclerosis and other related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2172851-58-8 |
| Applications | Apolipoprotein(a) Inhibitor |
| Formula | C296H419N71Na20O163P20S13 |
| Molecular Weight | 8636 (free acid) |
| Synonyms | AKCEA-APO(a)-LRx sodium; ISIS 681257 sodium; TQJ230 sodium |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.