Fig. 1 · Structure

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Pelacarsen

Apolipoprotein(a) Inhibitor

Pelacarsen is an apolipoprotein(a) inhibitor that functions as a GalNAc3-conjugated 2′-MOE-modified antisense oligonucleotide. This compound effectively reduces levels of apolipoprotein(a), making it valuable in research focused on lipid metabolism and cardiovascular diseases. It is commonly utilized in studies addressing dyslipidemia and atherogenic conditions linked to elevated lipoprotein(a) levels.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1637637-70-7
Applications Apolipoprotein(a) Inhibitor
Molecular Weight 8636.00
Synonyms AKCEA-APO(a)-LRx; ISIS 681257; TQJ230

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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