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Pepstatin acetate

Aspartic Protease Inhibitor

Pepstatin acetate is a potent aspartic protease inhibitor derived from actinomycetes, exhibiting a range of IC50 values, including 4.5 nM for hemoglobin-pepsin and 6.2 nM for hemoglobin-proctase. It selectively inhibits various proteolytic activities, including those of casein-pepsin and HIV protease. This compound is valuable for studies investigating protease function and inhibition, with potential applications in enzyme regulation, cancer research, and HIV treatment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	28575-34-0
Applications	Aspartic Protease Inhibitor
Formula	C₃₆H₆₇N₅O₁₁
Molecular Weight	745.94
Synonyms	Pepstatin A acetate
SMILES	CC(O)=O.CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)[C@@H](O)CC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.