Perfluoroenanthic acid-13C4 is a stable isotope labeled variant of Perfluoroenanthic acid, a perfluoroalkyl substance (PFAS) known for its significant biological implications. This compound has been shown to adversely affect the development of seminiferous tubules and influence m6A RNA methylation in the testes of offspring mice following maternal exposure, which disrupts spermatogenesis and contributes to reproductive toxicity. Additionally, Perfluoroenanthic acid alters dendritic spine morphology and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity, synaptic transmission, and elevating the expression of key excitatory synapse-related proteins, such as Synaptophysin and PSD95, making it valuable for research in neurobiology and developmental toxicology.
Perfluoroenanthic acid-13C4 is a stable isotope labeled variant of Perfluoroenanthic acid, a perfluoroalkyl substance (PFAS) known for its significant biological implications. This compound has been shown to adversely affect the development of seminiferous tubules and influence m6A RNA methylation in the testes of offspring mice following maternal exposure, which disrupts spermatogenesis and contributes to reproductive toxicity. Additionally, Perfluoroenanthic acid alters dendritic spine morphology and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity, synaptic transmission, and elevating the expression of key excitatory synapse-related proteins, such as Synaptophysin and PSD95, making it valuable for research in neurobiology and developmental toxicology.
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