PERK-IN-3 is a highly selective inhibitor of the Protein Kinase R (PKR)-like ER kinase (PERK) with an IC50 value of 7.4 nM. This compound effectively modulates the unfolded protein response, promoting cell survival under ER stress. It is primarily utilized in research investigating the role of PERK in cellular stress pathways, cancer biology, and neurodegenerative diseases.
PERK-IN-3 is a highly selective inhibitor of the Protein Kinase R (PKR)-like ER kinase (PERK) with an IC50 value of 7.4 nM. This compound effectively modulates the unfolded protein response, promoting cell survival under ER stress. It is primarily utilized in research investigating the role of PERK in cellular stress pathways, cancer biology, and neurodegenerative diseases.
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