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Pexelizumab
Pexelizumab (h5G1.1-SC) is a humanized single-chain variable fragment (scFv) monoclonal antibody that specifically targets the C5 component of the complement system. This antibody effectively inhibits key processes such as apoptosis and leukocyte infiltration, thereby modulating inflammatory responses. It is primarily utilized in research focused on cerebral ischemia-reperfusion (IR) injury and myocardial infarction, providing a valuable tool for investigating the role of the complement system in these conditions.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 219685-93-5 |
| Synonyms | h5G1. 1-SC |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.