Fig. 1 · Structure
Documents & Downloads
PF-03463275 hydrochloride
GlyT1 Inhibitor
PF-03463275 hydrochloride is a selective and competitive inhibitor of GlyT1 (glycine transporter-1), exhibiting a Ki of 11.6 nM. This compound is centrally penetrant and orally available, making it a valuable tool for research on synaptic transmission and neuropharmacology. PF-03463275 hydrochloride holds potential for advancing studies related to schizophrenia and other psychiatric disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1173177-11-1 |
| Applications | GlyT1 Inhibitor |
| Formula | C19H24Cl3FN4O |
| Molecular Weight | 449.78 |
| SMILES | O=C(C1=CN(C)C=N1)N(CC2=CC(Cl)=C(C=C2)F)C[C@@H]3[C@]4([H])[C@@]3([H])CN(C4)C.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.