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PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.46 mL | 67.29 mL | 134.59 mL |
| 0.5 mM | 2.69 mL | 13.46 mL | 26.92 mL |
| 1 mM | 1.35 mL | 6.73 mL | 13.46 mL |
| 5 mM | 0.27 mL | 1.35 mL | 2.69 mL |
*The above data is based on the productmolecular weight 743.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21858 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1436391-86-4 |
| Formula | C39H62N6O6S |
| M. Wt | 743.01 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | Aur0101, Aur-0101, Aur 0101; Auristatin-0101, Auristatin0101, Auristatin 0101, PF 06380101, PF06380101 |
| SMILES | CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C2=NC=CS2)CC3=CC=CC=C3)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC(C(C)(C)N)=O)=O)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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