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PF-06445974 precursor

PF-06445974 Precursor

PF-06445974 precursor is a nitro precursor and synthetic intermediate for the synthesis of PF-06445974, a potent positron emission tomography (PET) agent. PF-06445974 primarily targets phosphodiesterase 4B (PDE4B), offering valuable insights in neuroimaging and related biological research. This reagent is essential for studies involving PDE4B modulation and assessing its role in various physiological processes.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2055777-51-8
Applications	PF-06445974 Precursor
Formula	C₂₀H₁₅N₅O₃
Molecular Weight	373.36
SMILES	N#CC1=C([N+]([O-])=O)C=C(C2=C(C(N(C3CC3)CC4)=O)N4C5=C2N=CC=C5)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.