PF-06663195

Name: PF-06663195
Brand: Adooq Bioscience
SKU: A78502
Rating: 5 (288 reviews)

Catalog No.: A78502

BACE1 Inhibitor

PF-06663195 is a selective β-secretase 1 (BACE1) inhibitor, exhibiting IC50 values of 53 nM for the BACE1 CFA assay and 15 nM for the BACE1 WCA assay. This compound is a valuable tool for investigating the role of BACE1 in the pathogenesis of Alzheimer’s disease and can aid in the discovery of potential therapeutic strategies targeting amyloid precursor protein processing.

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PF-06663195 1621585-22-5 BACE1 Inhibitor

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Grouped product items
Size	Price	Stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PF-06663195 is a selective β-secretase 1 (BACE1) inhibitor, exhibiting IC50 values of 53 nM for the BACE1 CFA assay and 15 nM for the BACE1 WCA assay. This compound is a valuable tool for investigating the role of BACE1 in the pathogenesis of Alzheimer’s disease and can aid in the discovery of potential therapeutic strategies targeting amyloid precursor protein processing.

Product Information

Catalog Num	A78502
Formula	C18H18F3N3O2S
Molecular Weight	397.41
CAS Number	1621585-22-5
SMILES	FC[C@@H]1[C@@]2([H])[C@](N=C(S1)N)(C3=C(C=C(C=C3)F)F)CO[C@@H](C4=CC(C)=NO4)C2

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