Fig. 1 · Structure
Documents & Downloads
PF-06767832
Muscarinic M1 Agonist
PF-06767832 is a selective positive allosteric modulator of the muscarinic M1 receptor, exhibiting an EC50 value of 60 nM. This compound demonstrates favorable penetration into the central nervous system, enhancing M1 receptor signaling. It is primarily used in research focused on neuropharmacology, cognition, and potential treatments for cognitive disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1859081-58-5 |
| Applications | Muscarinic M1 Agonist |
| Formula | C22H23N3O3S |
| Molecular Weight | 409.50 |
| SMILES | O[C@@H](COCC1)[C@H]1NC(C2=CC(CC3=CC=C(C4=CSC=N4)C=C3)=C(C)C=N2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.