Fig. 1 · Structure
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PF-184298
Serotonin/Noradrenaline Reuptake Inhibitor
PF-184298 is a dual serotonin and noradrenaline reuptake inhibitor, exhibiting IC50 values of 6 nM for serotonin and 21 nM for noradrenaline. This compound demonstrates significant potential in modulating neurotransmitter levels, making it valuable for research into mood disorders and related neuropharmacological studies. Its mechanism of action provides insights into therapeutic strategies for conditions such as depression and anxiety.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 813447-40-4 |
| Applications | Serotonin/Noradrenaline Reuptake Inhibitor |
| Formula | C15H20Cl2N2O |
| Molecular Weight | 315.24 |
| SMILES | O=C(C1=CC=CC(Cl)=C1Cl)N([C@@H]2CNCC2)CC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.