Fig. 1 · Structure
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PF-9363
KAT6A/KAT6B Inhibitor
PF-9363 is a potent and highly selective inhibitor of KAT6A and KAT6B, two histone acetyltransferases involved in the regulation of gene expression. This compound exhibits significant biological activity in cancer research, making it a valuable tool for investigating the roles of these targets in tumorigenesis and cellular proliferation. PF-9363 is ideal for studies aimed at understanding the epigenetic mechanisms underlying cancer development and progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2569009-58-9 |
| Applications | KAT6A/KAT6B Inhibitor |
| Formula | C20H20N4O6S |
| Molecular Weight | 444.46 |
| Synonyms | CTx-648 |
| SMILES | O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2C(OC)=CC(CN4N=CC=C4)=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.