Fig. 1 · Structure
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PFI-7
GID4 Probe
PFI-7 is a specific probe that targets human GID4, exhibiting a binding affinity with a KD of 79 nM. This compound effectively antagonizes the interaction of Pro/N-degrons, making it a valuable tool for studies focused on the C-terminal to LisH (CTLH) complex. PFI-7 is useful in the exploration of mechanisms underlying targeted protein degradation, facilitating advancements in this area of research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2910938-58-6 |
| Applications | GID4 Probe |
| Formula | C24H27N5O |
| Molecular Weight | 401.50 |
| SMILES | O=C(N[C@@H]1CC[C@H](C2=NC(C=CC=C3)=C3N2)CC1)CNCC4=CC5=C(C=CC=C5)N4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.