Fig. 1 · Structure
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PGAM1-IN-2
Phosphatase Inhibitor
PGAM1-IN-2 is a potent phosphoglycerate mutase 1 (PGAM1) inhibitor, exhibiting an IC50 value of 2.1 μM. It effectively disrupts the enzymatic activity of PGAM1, which plays a critical role in glycolysis and metabolism. This compound is valuable for research applications involving cancer metabolism, metabolic disorders, and the investigation of therapeutic targets in glycolytic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2438637-66-0 |
| Applications | Phosphatase Inhibitor |
| Formula | C25H16N2O7S |
| Molecular Weight | 488.47 |
| SMILES | O=C1C2=C(O)C=C(NS(C3=CC=C(C4=CC=CC=C4)C=C3)(=O)=O)C=C2OC5=C1C=C([N+]([O-])=O)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.