PGN-9856 is a selective agonist of the EP2 receptor, exhibiting high affinity with a pKi of 8.3 or greater. This potent non-prostanoid compound demonstrates significant biological activity, with an EC50 value of 8.5 or higher, making it effective in anti-inflammatory and anti-glaucoma research applications. PGN-9856 serves as a valuable tool for exploring the therapeutic potential of targeting the EP2 receptor in various pharmacological studies.
PGN-9856 is a selective agonist of the EP2 receptor, exhibiting high affinity with a pKi of 8.3 or greater. This potent non-prostanoid compound demonstrates significant biological activity, with an EC50 value of 8.5 or higher, making it effective in anti-inflammatory and anti-glaucoma research applications. PGN-9856 serves as a valuable tool for exploring the therapeutic potential of targeting the EP2 receptor in various pharmacological studies.
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