PHA-767491 hydrochloride

Catalog No.: A21395

dual Cdc7/Cdk9 inhibitor

PHA-767491 hydrochloride

PHA-767491 hydrochloride Chemical Structure

CAS NO. 942425-68-5

PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively.

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Biological Activity

PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively.
In vitro (25°C) DMSO 24 mg/mL (96.11 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.05 mL 200.24 mL 400.48 mL
0.5 mM 8.01 mL 40.05 mL 80.1 mL
1 mM 4 mL 20.02 mL 40.05 mL
5 mM 0.8 mL 4 mL 8.01 mL

*The above data is based on the productmolecular weight 249.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21395
Actions Inhibitor
CAS No. 942425-68-5
Formula C12H12ClN3O
M. Wt 249.7
Solubility DMSO
Purity >98%
Synonyms PHA767491, PHA 767491, CAY-10572 hydrochloride, CAY10572, CAY 10572

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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