PHA-767491

Catalog No.: A11164

Cdc7/cdk9 inhibitor

PHA-767491 Chemical Structure

CAS NO. 845714-00-3

PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

Availability: In stock

Package Price Qty
10 mg
$70.00
50 mg
$280.00
100 mg
$490.00
10mM * 1mL in DMSO
$76.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

In vitro (25°C) DMSO 24 mg/mL (112.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.9 mL 234.48 mL 468.96 mL
0.5 mM 9.38 mL 46.9 mL 93.79 mL
1 mM 4.69 mL 23.45 mL 46.9 mL
5 mM 0.94 mL 4.69 mL 9.38 mL

*The above data is based on the productmolecular weight 213.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11164
Actions Inhibitor
M. Wt 213.24
Formula C12H11N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 845714-00-3
Synonyms PHA767491
SMILES C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3

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