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$0.00 - Qi Li, .et al. CDC7-dependent transcriptional regulation of RAD54L is essential for tumorigenicity and radio-resistance of glioblastoma, Transl Oncol, 2018, Apr; 11(2): 300-306 PMID: 29413763
Biological Activity
PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 46.9 mL | 234.48 mL | 468.96 mL |
| 0.5 mM | 9.38 mL | 46.9 mL | 93.79 mL |
| 1 mM | 4.69 mL | 23.45 mL | 46.9 mL |
| 5 mM | 0.94 mL | 4.69 mL | 9.38 mL |
*The above data is based on the productmolecular weight 213.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11164 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 845714-00-3 |
| Formula | C12H11N3O |
| M. Wt | 213.24 |
| Purity | >98% |
| Synonyms | PHA767491 |
| SMILES | C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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