Fig. 1 · Structure
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Phe8Ψ(CH-NH)Arg9-Bradykinin
Bradykinin receptor B2 Agonist
[Phe8Ψ(CH-NH)Arg9]-Bradykinin is a selective agonist of the Bradykinin receptor B2, demonstrating resistance to cleavage by protein kinase I/II. This compound exhibits significant biological activity relevant to cardiovascular research, particularly in the study of hypertension. Its ability to selectively activate the B2 receptor positions it as a valuable tool for investigating bradykinin-related pathways in various physiological and pathological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 118122-39-7 |
| Applications | Bradykinin receptor B2 Agonist |
| Formula | C50H75N15O10 |
| Molecular Weight | 1046.23 |
| SMILES | C(=O)([C@H]1N(C([C@H](CCCNC(=N)N)N)=O)CCC1)N2[C@H](C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(=O)N4[C@H](C(N[C@@H](CC5=CC=CC=C5)CN[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC4)CO)=O)=O)=O)CCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.