(±)Phenserine ((±)-Eseroline phenylcarbamate)

Catalog No.: A78446
Phenserine Racemic Form
(±)Phenserine is a racemic form of the acetylcholinesterase (AChE) inhibitor Phenserine, derived from Physostigmine. This compound exhibits non-competitive and long-lasting inhibition of AChE, leading to a decrease in the formation of β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ). (±)Phenserine has been shown to enhance cognitive abilities and may help to slow the progression of Alzheimer's disease, making it a valuable agent in neurodegenerative research.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(±)Phenserine is a racemic form of the acetylcholinesterase (AChE) inhibitor Phenserine, derived from Physostigmine. This compound exhibits non-competitive and long-lasting inhibition of AChE, leading to a decrease in the formation of β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ). (±)Phenserine has been shown to enhance cognitive abilities and may help to slow the progression of Alzheimer's disease, making it a valuable agent in neurodegenerative research.
Product Information
Catalog NumA78446
FormulaC20H23N3O2
Molecular Weight337.42
CAS Number159652-53-6
SMILESC[C@@]12C3=CC(OC(NC4=CC=CC=C4)=O)=CC=C3N([C@]1([H])N(CC2)C)C
Synonyms(±)-Eseroline phenylcarbamate
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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