Phosphatidylglycerols (egg) sodium salt is a biochemical assay reagent that selectively targets the TLR4 accessory protein CD14/MD-2 complex, effectively inhibiting LPS or virus-mediated inflammatory signaling pathways through competitive binding. This compound directly interacts with viral particles, blocking infection and reducing COX-2 expression to lower the release of inflammatory cytokines such as IL-6 and IL-8. Additionally, it enhances oxidative stress response by promoting mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols are applicable in research related to chronic inflammatory diseases, including atherosclerosis, and respiratory viral infections such as RSV.
Phosphatidylglycerols (egg) sodium salt is a biochemical assay reagent that selectively targets the TLR4 accessory protein CD14/MD-2 complex, effectively inhibiting LPS or virus-mediated inflammatory signaling pathways through competitive binding. This compound directly interacts with viral particles, blocking infection and reducing COX-2 expression to lower the release of inflammatory cytokines such as IL-6 and IL-8. Additionally, it enhances oxidative stress response by promoting mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols are applicable in research related to chronic inflammatory diseases, including atherosclerosis, and respiratory viral infections such as RSV.
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