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Phyllomedusin

Catalog No.: A62039
NK1 Receptor Agonist
Phyllomedusin is a tachykinin decapeptide that acts as an NK1 receptor agonist. It exhibits vasodilating properties and induces contraction of the pylorus, making it valuable for studying gastrointestinal motility and vascular biology. Research applications include investigations into neurokinin signaling pathways and potential therapeutic approaches for modulating blood flow and gut function.
Phyllomedusin 26145-48-2 NK1 Receptor Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPhyllomedusin is a tachykinin decapeptide that acts as an NK1 receptor agonist. It exhibits vasodilating properties and induces contraction of the pylorus, making it valuable for studying gastrointestinal motility and vascular biology. Research applications include investigations into neurokinin signaling pathways and potential therapeutic approaches for modulating blood flow and gut function.
Product Information
Catalog NumA62039
FormulaC52H82N16O13S
Molecular Weight1171.37
CAS Number26145-48-2
Sequence shortening{Pyr}-NPNRFIGLM-NH2
SMILESC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC2
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GPCR/G Protein > Neurokinin Receptors