PI-1840

Catalog No.: A14146

reversible proteasome inhibitor

PI-1840

PI-1840 Chemical Structure

CAS NO. 1401223-22-0

PI-1840 is a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $320.00

Special Price $256.00

10mM * 1mL in DMSO

Regular Price: $95.00

Special Price $76.00

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Biological Activity

PI-1840 is a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.
Targets
Chymotrypsin-like proteasome
27 nM
In vitro DMSO 77 mg/mL (195.2 mM)
Water Insoluble
Ethanol 33 mg/mL (83.65 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.51 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.467. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14146
Actions Inhibitor
CAS No. 1401223-22-0
Formula C22H26N4O3
M. Wt 394.467
Purity >98%
Synonyms PI 1840, PI1840
SMILES CCCC1=CC=C(C=C1)OCC(=O)N(CC2=NC(=NO2)C3=CN=CC=C3)C(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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