Akt

Cat. No.

A25595

CAS No.

324029-01-8

AKTide-2T

AKTide-2T is a selective substrate for AKT, demonstrating competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. This peptide mimics the optimal phosphorylation sequence of Akt, effectively serving as an inhibitory agent due to the absence of Thr at the S22 position in the wildtype sequence. It is a valuable tool for studying AKT signaling pathways and their implications in various biological processes.

Cat. No.

A25725

CAS No.

276680-69-4

Akt/SKG Substrate Peptide

Akt/SKG Substrate Peptide is a synthetic peptide specifically designed as a substrate for Akt/PKB. This peptide is selectively phosphorylated by Akt/PKB and does not undergo phosphorylation by p70S6K or MAPK1, making it an ideal tool for studying the Akt signaling pathway. Its specificity is valuable in research applications focused on cancer, metabolism, and neurological disorders associated with Akt dysregulation.

Cat. No.

A25949

CAS No.

171783-05-4

Crosstide

Crosstide is a peptide analog derived from the glycogen synthase kinase α/β fusion protein sequence, serving as a substrate for Akt. This compound is widely used in research to investigate Akt signaling pathways and assess kinase activity. Crosstide facilitates studies focused on cellular metabolism, growth, and survival, providing valuable insights into the roles of Akt in various biological processes and diseases.

Cat. No.

A86466

CAS No.

9010-34-8

Thyroglobulin

Synonyms: Thyroglobulin from bovine

Thyroglobulin is a 660 kDa dimeric glycoprotein that serves as a substrate in the synthesis of thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Primarily produced by follicular cells of the thyroid, it also functions in the storage of inactive thyroid hormone forms and iodine in the follicular lumen. In research applications, thyroglobulin has been shown to activate Akt kinase activity in FRTL-5 thyroid cells, making it valuable for studies related to thyroid function and signaling pathways.