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Piericidin A

Mitochondrial Complex I Inhibitor

Piericidin A is a potent inhibitor of mitochondrial Complex I (NADH-ubiquinone oxidoreductase), effectively disrupting mitochondrial respiration by interfering with the electron transport chain. This compound exhibits neurotoxic properties and has been shown to inhibit quorum sensing, thus reducing the expression of virulence genes in Erwinia carotovora subsp. atroseptica. Additionally, Piericidin A serves as an ADC cytotoxin and presents various biological activities, including antibacterial and anticancer effects, making it valuable for diverse research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2738-64-9
Applications	Mitochondrial Complex I Inhibitor
Formula	C₂₅H₃₇NO₄
Molecular Weight	415.57
Synonyms	AR-054
SMILES	COC1=C(C(C)=C(N=C1OC)C/C=C(C/C=C/C(C)=C/[C@@H](C)[C@H](/C(C)=C/C)O)\C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.