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Biological Activity
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.47 mL | 147.34 mL | 294.68 mL |
| 0.5 mM | 5.89 mL | 29.47 mL | 58.94 mL |
| 1 mM | 2.95 mL | 14.73 mL | 29.47 mL |
| 5 mM | 0.59 mL | 2.95 mL | 5.89 mL |
*The above data is based on the productmolecular weight 339.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11476 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1093222-27-5 |
| Formula | C20H13N5O |
| M. Wt | 339.35 |
| Purity | >98% |
| Synonyms | LKB1/AAK1 dual inhibitor |
| SMILES | N#CC1=CC=C(C2=CN=C3C(C(NC(C4=CC=CN=C4)=O)=CN3)=C2)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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