(-)-Pinoresinol 4-O-glucoside serves as a potent α-glucosidase inhibitor, exhibiting an IC50 value of 48.13 µM. This compound promotes cell migration and early differentiation of pre-osteoblasts while enhancing the protein levels of BMP2, phosphorylated Smad1/5/8, and RUNX2. Additionally, it demonstrates protective effects against oxidative stress, hyperglycemia, and hepatic toxicity. (-)-Pinoresinol 4-O-glucoside is a valuable reagent for investigating osteoporosis and periodontal disease.
(-)-Pinoresinol 4-O-glucoside serves as a potent α-glucosidase inhibitor, exhibiting an IC50 value of 48.13 µM. This compound promotes cell migration and early differentiation of pre-osteoblasts while enhancing the protein levels of BMP2, phosphorylated Smad1/5/8, and RUNX2. Additionally, it demonstrates protective effects against oxidative stress, hyperglycemia, and hepatic toxicity. (-)-Pinoresinol 4-O-glucoside is a valuable reagent for investigating osteoporosis and periodontal disease.
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