PKMYT1-IN-11 is a potent inhibitor of PKMYT1, exhibiting an IC50 of 4.49 nM. This compound effectively suppresses the proliferation of HCC1569 cancer cells and demonstrates a significant anti-tumor effect in combination with Gemcitabine in the OVCAR3 xenograft mouse model. PKMYT1-IN-11 is valuable for researching various cancers, including breast and ovarian cancer, providing insights into therapeutic strategies targeting PKMYT1.
PKMYT1-IN-11 is a potent inhibitor of PKMYT1, exhibiting an IC50 of 4.49 nM. This compound effectively suppresses the proliferation of HCC1569 cancer cells and demonstrates a significant anti-tumor effect in combination with Gemcitabine in the OVCAR3 xenograft mouse model. PKMYT1-IN-11 is valuable for researching various cancers, including breast and ovarian cancer, providing insights into therapeutic strategies targeting PKMYT1.
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