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Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.99 mL | 189.97 mL | 379.94 mL |
| 0.5 mM | 7.6 mL | 37.99 mL | 75.99 mL |
| 1 mM | 3.8 mL | 19 mL | 37.99 mL |
| 5 mM | 0.76 mL | 3.8 mL | 7.6 mL |
*The above data is based on the productmolecular weight 263.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11434 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 263.2 |
| Formula | C9H11F2N3O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 95058-81-4 |
| Synonyms | LY 188011, LY188011, LY-188011 |
| SMILES | O=C1N(C=CC(N)=N1)[[email protected]]2C(F)([[email protected]@H]([[email protected]](O2)CO)O)F |
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