Gemcitabine

Catalog No.: A11434

DNA synthesis inhibitor

Gemcitabine

Gemcitabine Chemical Structure

CAS NO. 95058-81-4

Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.

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100 mg
$45.00
500 mg
$135.00
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Biological Activity

Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.99 mL 189.97 mL 379.94 mL
0.5 mM 7.6 mL 37.99 mL 75.99 mL
1 mM 3.8 mL 19 mL 37.99 mL
5 mM 0.76 mL 3.8 mL 7.6 mL

*The above data is based on the productmolecular weight 263.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11434
Actions Inhibitor
M. Wt 263.2
Formula C9H11F2N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 95058-81-4
Synonyms LY 188011, LY188011, LY-188011
SMILES O=C1N(C=CC(N)=N1)[[email protected]]2C(F)([[email protected]@H]([[email protected]](O2)CO)O)F

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