Plasma kallikrein-IN-1

Catalog No.: A64974
Ser/Thr Protease Activator
Plasma kallikrein-IN-1 is a highly potent inhibitor of plasma kallikrein, exhibiting an IC50 of 0.5 nM. This compound selectively targets serine/threonine proteases, thereby modulating proteolytic pathways. It is primarily utilized in research exploring the roles of kallikrein in cardiovascular and inflammatory disorders. This compound is invaluable for studies aimed at understanding the therapeutic potential of kallikrein inhibition.
Grouped product items
Size Price Stock Qty
5mg
$795.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPlasma kallikrein-IN-1 is a highly potent inhibitor of plasma kallikrein, exhibiting an IC50 of 0.5 nM. This compound selectively targets serine/threonine proteases, thereby modulating proteolytic pathways. It is primarily utilized in research exploring the roles of kallikrein in cardiovascular and inflammatory disorders. This compound is invaluable for studies aimed at understanding the therapeutic potential of kallikrein inhibition.
Product Information
Catalog NumA64974
FormulaC23H25F2N7O
Molecular Weight453.49
CAS Number2691030-28-9
SMILESFC(F)C1=C(C=CC(N2CC3(CC3)C2)=N1)CN4C=NC(C(N[C@@H]5CCC6=C(C)NN=C65)=O)=C4
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