Fig. 1 · Structure
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PLpro-IN-5
PLPro Protease Inhibitor
PLpro-IN-5 is a potent inhibitor of the PLPro protease, exhibiting an IC50 value of 91.14 nM. This compound demonstrates broad-spectrum antiviral activity, particularly against coronaviruses such as SARS-CoV, MERS-CoV, and SARS-CoV-2. It serves as a valuable tool in research aimed at understanding and combating viral infections associated with these pathogens.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3009839-42-0 |
| Applications | PLPro Protease Inhibitor |
| Formula | C26H33N3O |
| Molecular Weight | 403.56 |
| SMILES | O=C(C1=CC(N2CC(C2)N(C)C)=CC=C1C)NC3(CC3)C4=C(CCCC5)C5=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.