Fig. 1 · Structure

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PLpro-IN-6

PLpro Inhibitor

PLpro-IN-6 is a potent inhibitor of the papain-like protease (PLpro) with an IC50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme. This compound demonstrates significant antiviral activity, making it a valuable tool for research into therapeutic strategies targeting SARS-CoV-2. PLpro-IN-6 is suitable for studies focused on viral replication and the development of novel antiviral therapies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3041046-04-9
Applications PLpro Inhibitor
Formula C29H30N6O
Molecular Weight 478.59
SMILES
CC1=CC(CNCC2=NC=CN2)=CC=C1C(NC(C3=C(C=CC=C4)C4=CC(C5=CN(C)N=C5)=C3)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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