Fig. 1 · Structure
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Polycarbophil
Pharmaceutical Excipient
Polycarbophil is a hydrophilic polymer that primarily serves as a pharmaceutical excipient. Its mechanism involves bioadhesion facilitated by hydrogen bonding between carboxyl groups and mucosal surfaces, which enhances retention time and regulates the release of encapsulated compounds through its swelling properties. This compound is well-documented for its utility in alleviating both constipation and diarrhea, making it valuable in gastrointestinal research and formulation development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9003-97-8 |
| Applications | Pharmaceutical Excipient |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.