Pharmaceutical Excipients

Cat. No.

A11365

CAS No.

182410-00-0

SBE-β-CD

Synonyms: Sulfobutylether-β-Cyclodextrin

SBE-β-CD is a sulfobutylether derivative of β-cyclodextrin primarily utilized as an excipient in pharmaceutical formulations. It enhances the solubility of poorly soluble compounds, thereby improving their bioavailability. SBE-β-CD is valuable in drug development, particularly for improving the delivery of hydrophobic agents in various therapeutic applications.

Cat. No.

A16579

CAS No.

9004-64-2

Hydroxypropyl Cellulose

Hydroxypropyl Cellulose (HPC) functions as a pharmaceutical excipient with surfactant properties. This cellulose ether exhibits anti-inflammatory activity by reducing mediators such as IL-6 and IL-1β, contributing to improvements in conditions like colitis and obesity. HPC serves as a versatile agent in drug formulation, being used in applications such as coating agents, emulsifiers, suspensions, tablets, thickeners, and viscosifiers, facilitating enhanced drug delivery and stability.

Cat. No.

A17310

CAS No.

532-32-1

Sodium benzoate

Sodium benzoate functions as a pharmaceutical excipient with multiple roles, including serving as an antibacterial agent and preservative. It enhances the stability, solubility, and processability of drug formulations while potentially influencing the absorption, distribution, metabolism, and elimination (ADME) of co-administered compounds. Additionally, sodium benzoate activates the NF-κB signaling pathway, induces apoptosis, and has been studied for its immunosuppressive effects as well as reproductive toxicity. Its applications extend to research in colon cancer and immune diseases.

Cat. No.

A33172

CAS No.

7758-11-4

Dipotassium hydrogen phosphate

Dipotassium hydrogen phosphate is a phosphate salt that serves as an effective pharmaceutical excipient. It acts primarily as a pH adjuster and buffer, facilitating optimal conditions for various biochemical reactions. Additionally, dipotassium hydrogen phosphate has been shown to enhance lipase production in Rhizopus oligosporus, underscoring its utility in microbial fermentation studies and bioprocessing applications.

Cat. No.

A59874

CAS No.

8030-76-0

Soya Lecithin

Soya Lecithin is a phospholipid mixture primarily used as a pharmaceutical excipient and drug delivery vehicle. Its amphiphilic properties enable the formation of lipid bilayer structures, allowing for the encapsulation of hydrophobic drugs. By forming stable nanoliposomes or microemulsions, Soya Lecithin enhances the solubility and cellular uptake of poorly soluble compounds, thereby improving drug delivery efficiency and potentially regulating cell proliferation. This makes it a valuable reagent for various drug formulation applications in chemical and pharmaceutical research.

Cat. No.

A71276

CAS No.

9004-34-6

Cellulose

Synonyms: Pectin glycosidase

Cellulose is a natural high molecular weight polysaccharide primarily utilized as a pharmaceutical excipient. Its biocompatibility and biodegradability allow for versatile applications in drug formulation, enhancing stability and improving the delivery of active ingredients. Additionally, Cellulose serves as a critical component in the production of cellulose derivatives, such as cellulose acetate and cellulose nitrate, and is commonly employed in the food industry as a functional additive to enhance food quality.

Cat. No.

A73929

CAS No.

112-92-5

1-Hydroxyoctadecane

Synonyms: Stearyl alcohol

1-Hydroxyoctadecane, a long-chain fatty alcohol, serves as an effective excipient in pharmaceutical formulations. It creates a protective oil film that reduces transepidermal water loss (TEWL), thus enhancing skin hydration and moisturization. Additionally, 1-Hydroxyoctadecane has demonstrated efficacy in improving Imiquimod-induced psoriatic skin inflammation in murine models, making it a valuable compound for dermatological research applications.

Cat. No.

A75887

CAS No.

99387-94-7

Dilaurylglycerosulfate

Dilaurylglycerosulfate functions as a co-emulsifier, primarily utilized in diagnostic assays for the measurement of lipase activity. Its unique properties enhance the stability and performance of emulsions in various biochemical reactions, making it a valuable reagent for clinical diagnostics and research focusing on lipid metabolism. This compound is instrumental in the accurate determination of lipase, contributing to improved diagnostic outcomes.

Cat. No.

A75889

CAS No.

99388-09-7

Dilaurylglycerosulfate sodium

Dilaurylglycerosulfate sodium acts as a co-emulsifier and is primarily utilized in diagnostic tests to determine lipase activity. This reagent stabilizes emulsions, facilitating accurate measurement in enzymatic assays. Its role is critical in enhancing the reliability of lipase quantification in various clinical and biochemical applications.

Cat. No.

A75943

CAS No.

1849616-42-7

ALC-0159

ALC-0159 is a polyethylene glycol (PEG) lipid conjugate that serves as a vaccine excipient. Its incorporation enhances the stability and delivery of vaccine formulations by facilitating the encapsulation of active pharmaceutical ingredients. ALC-0159 is particularly useful in the development of lipid nanoparticles and other innovative drug delivery systems, contributing to improved immunogenicity and efficacy in vaccine applications.

Cat. No.

A76046

CAS No.

2036272-50-9

1,19-Bis(2-butyloctyl) 10-[[3-(dimethylamino)propyl](1-oxononyl)amino]nonadecanedioate

1,19-Bis(2-butyloctyl) 10-[[3-(dimethylamino)propyl](1-oxononyl)amino]nonadecanedioate serves as a vital excipient in vaccine formulations. This compound enhances the stability and delivery efficiency of vaccine components, playing a critical role in the development of COVID-19 vaccines and other immunotherapeutic applications. Its unique structural properties facilitate effective gene delivery, making it valuable in advancing gene therapy research and applications.

Cat. No.

A76093

CAS No.

142-91-6

Isopropyl palmitate

Synonyms: Propan-2-yl hexadecanoate

Isopropyl palmitate is a fatty acid ester primarily used as a pharmaceutical excipient. It demonstrates significant biological activity by forming bioactive bilayer films that can scavenge free radicals and inhibit lipid peroxidation, along with suppressing the growth of foodborne pathogens. As an excipient, it serves various roles including a lubricant, oily carrier, solvent, and component in controlled-release transdermal films. Isopropyl palmitate enhances the stability, solubility, and overall processability of pharmaceutical preparations while influencing the absorption, distribution, metabolism, and elimination (ADME) profiles of co-administered drugs.

Cat. No.

A76324

CAS No.

26658-19-5

Sorbitan tristearate

Sorbitan tristearate serves as a non-ionic surfactant that enhances skin permeability through its emulsifying properties. This compound functions as a pharmaceutical excipient, improving the stability, solubility, and processability of various formulations. Additionally, sorbitan tristearate can influence the absorption, distribution, metabolism, and elimination (ADME) of co-administered drugs, making it a valuable component in drug development and delivery systems.

Cat. No.

A86435

CAS No.

9004-65-3

HPMC (Viscosity:11250-21000mPa.s)

Synonyms: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)

Hydroxypropyl Methylcellulose (HPMC) is a hydrophilic, non-ionic cellulose ether primarily utilized as an excipient in various pharmaceutical formulations. With a viscosity range of 11250-21000 mPa.s, HPMC enables the creation of swellable-soluble matrices, enhancing drug delivery by controlling release profiles. Its unique properties make it ideal for applications in oral, topical, and controlled-release systems.

Cat. No.

A86455

CAS No.

29894-35-7

Polyglycerol-polyricinoleate

Synonyms: PGPR

Polyglycerol-polyricinoleate (PGPR) functions as an effective emulsifier, primarily utilized in food formulations. This compound enhances the texture and stability of various food products, contributing to improved quality and shelf-life. Additionally, PGPR is applicable in research areas focusing on food science, material science, and formulation development.

Cat. No.

A86510

CAS No.

7558-80-7

Anhydrous sodium dihydrogen phosphate

Synonyms: Sodium phosphate monobasic; Monosodium dihydrogen orthophosphate; Monosodium phosphate

Anhydrous sodium dihydrogen phosphate serves as an essential pharmaceutical excipient with buffering capabilities. It is widely employed in various industries, including pharmaceuticals and chemical processing, due to its ability to stabilize pH in formulations. Additionally, this compound is utilized in water treatment applications, functioning as a purifying and precipitating agent to enhance environmental protection efforts. Its versatility makes it critical for both laboratory and industrial applications.

Cat. No.

A86723

CAS No.

8002-03-7

Peanut Oil

Peanut Oil serves as a pharmaceutical excipient, enhancing the formulation of drug preparations. This inactive ingredient is instrumental in improving the stability, solubility, and overall processability of pharmaceutical products. Additionally, Peanut Oil plays a significant role in modulating the absorption, distribution, metabolism, and elimination (ADME) of co-administered compounds, thereby influencing their therapeutic efficacy and safety profiles.

Cat. No.

A86751

CAS No.

1338-43-8

Sorbitan monooleate

Sorbitan monooleate is a non-ionic emulsifier that facilitates the formation and stabilization of emulsions. It exhibits excellent biocompatibility and is commonly utilized in both food technology and pharmaceutical formulations as an excipient. Its ability to improve the texture and stability of mixtures makes it a valuable reagent in various biological and chemical research applications.

Cat. No.

A86865

CAS No.

8009-03-8

Petrolatum (white)

Petrolatum (white) is a pharmaceutical excipient widely utilized as an ointment vehicle due to its minimal skin irritation properties. This inert, hydrophobic compound serves as an effective barrier for wound care, facilitating healing in ambulatory surgical applications. It is specifically designed to enhance the stability and delivery of active pharmaceutical ingredients in topical formulations.

Cat. No.

A86899

CAS No.

9004-57-3

Ethyl cellulose

Synonyms: Ethyl cellulose N-200

Ethyl cellulose is a non-toxic, biodegradable polymer derived from cellulose, primarily utilized as a pharmaceutical excipient. It exhibits beneficial properties, including the formation of oil gels, delivery of active ingredients, and film formation. Common research applications include its use as a coating agent, flavoring agent, and tablet filler, as well as its role in the preparation of nanoparticles for enhanced active compound delivery.

Cat. No.

A87084

CAS No.

16788-57-1

Dipotassium hydrogen phosphate trihydrate

Dipotassium hydrogen phosphate trihydrate acts as a pharmaceutical excipient and is utilized primarily as a buffering agent and a source of both phosphorus and potassium. This compound is essential in the preparation of cell culture media and reagent buffer systems within biochemistry and molecular biology applications. Additionally, it serves as a reagent in analytical chemistry for the determination of calcium and magnesium ions in water samples, making it a valuable tool in various research settings.

Cat. No.

A87135

CAS No.

61790-53-2

Celite

Synonyms: Diatomaceous earth

Celite is a pharmaceutical excipient primarily utilized as a filter media and adsorbent. It plays a critical role in the pharmaceutical formulation process by enhancing the stability, solubility, and processability of active ingredients. Additionally, Celite can influence the absorption, distribution, metabolism, and elimination (ADME) of co-administered drugs, making it an essential component in drug delivery systems and pharmaceutical preparations.

Cat. No.

A87255

CAS No.

74811-65-7

Croscarmellose sodium

Croscarmellose sodium is a pharmaceutical excipient primarily utilized as a disintegrant. This compound enhances the dissolution of solid dosage forms, facilitating the release of active pharmaceutical ingredients. Its multifunctional properties include serving as a suspending agent, binder, glidant, and antiadherent. Croscarmellose sodium is integral in the formulation of various pharmaceutical applications to improve bioavailability and ensure optimal drug performance.

Cat. No.

A87259

CAS No.

9050-36-6

Maltodextrin, dextrose equivalent 16.5-19.5

Synonyms: Maltodextrin; Dextrin maize starch

Maltodextrin, dextrose equivalent 16.5-19.5, functions primarily as a pharmaceutical excipient. This compound plays a vital role in enhancing the stability, solubility, and processability of pharmaceutical formulations. Additionally, it can influence the absorption, distribution, metabolism, and elimination (ADME) profiles of co-administered active pharmaceutical ingredients. Maltodextrin is widely utilized in the development of various drug formulations, ensuring improved performance and efficacy in therapeutic applications.

Cat. No.

A87562

CAS No.

557-04-0

Magnesium stearate

Synonyms: Stearic Acid Magnesium(II) Salt

Magnesium stearate is an effective pharmaceutical excipient primarily utilized as a lubricant in tablet formulations. While it enhances the flow properties and processing of powders, it may adversely affect the bonding between particles. This inactive ingredient is crucial for improving the stability and solubility of pharmaceutical preparations, thereby influencing the absorption, distribution, metabolism, and elimination (ADME) of co-administered drugs. Its role as an excipient is vital in ensuring optimal performance and efficacy in drug delivery systems.