Fig. 1 · Structure
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Potassium (2-((tert-butoxycarbonyl)amino)ethyl)trifluoroborate
PROTAC Linker
Potassium (2-((tert-butoxycarbonyl)amino)ethyl)trifluoroborate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its unique chemical structure aids in conjugating E3 ligases with target proteins, enabling targeted degradation pathways. This compound is essential for research applications focusing on targeted protein degradation and therapeutic development in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 926280-83-3 |
| Applications | PROTAC Linker |
| Formula | C7H14BF3KNO2 |
| Molecular Weight | 251.10 |
| SMILES | [K+].O=C(OC(C)(C)C)NC[CH2-][B+3]([F-])([F-])[F-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.