Pozanicline

Catalog No.: A21318
Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at ??4??2* nAChRs (Ki=16 nM) and shows high selectivity for ??6??2* and ??4??5??2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM.
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Product Name Price Stock Qty
Pozanicline 1mg
$320.00
In stock
Pozanicline 5mg
$960.00
In stock
Pozanicline 10mg
$1,600.00
In stock
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Biological Activity
Discription Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at ??4??2* nAChRs (Ki=16 nM) and shows high selectivity for ??6??2* and ??4??5??2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM.
Product Information
Catalog Num A21318
Formula C11H16N2O
Molecular Weight 192.26
CAS Number 161417-03-4
SMILES CC1=C(OC[C@H]2NCCC2)C=CC=N1
Synonyms ABT-089
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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