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Pozelimab
Pozelimab (REGN3918) is a fully humanized IgG4 monoclonal antibody specifically developed to target and bind with high affinity to complement component 5 (C5) and its variants. This antibody effectively inhibits the cleavage of C5, thereby blocking complement-mediated hemolysis. It is an essential tool for investigating the pathophysiology of complement-mediated disorders and is suitable for use in various research settings focused on these diseases.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2096328-94-6 |
| Molecular Weight | 144780 |
| Synonyms | REGN3918 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.