Fig. 1 · Structure
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(±)-PPCC
Sigma-1 Agonist
(±)-PPCC is a potent sigma-1 receptor agonist, exhibiting a binding affinity with a Ki value of 1.5 nM. This compound demonstrates significant anti-amnesic effects in both mild and severe cognitive impairment models in rats, leading to marked improvements in cognitive function. Its utility in neurological research makes it a valuable tool for studying the mechanisms underlying cognitive disorders and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 932736-90-8 |
| Applications | Sigma-1 Agonist |
| Formula | C24H29NO3 |
| Molecular Weight | 379.49 |
| SMILES | COC([C@]1(C2=CC=C(C=C2)C)[C@@H](C1)CN3CCC(CC3)(C4=CC=CC=C4)O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.