PPM-3

Name: PPM-3
Brand: Adooq Bioscience
SKU: A36667
Rating: 5 (288 reviews)

Catalog No.: A36667

PROTAC ERK5 Degrader

PPM-3 is a potent and selective PROTAC degrader of ERK5, exhibiting an IC50 of 62.4 nM. While PPM-3 does not directly affect tumor cell proliferation, it modulates tumor development by impacting macrophage differentiation. This compound may serve as a valuable tool for investigating the role of ERK5 degradation in cancer biology and immune modulation.

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Size	Price	Stock
1mg	$220.00	In stock
5mg	$685.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PPM-3 is a potent and selective PROTAC degrader of ERK5, exhibiting an IC50 of 62.4 nM. While PPM-3 does not directly affect tumor cell proliferation, it modulates tumor development by impacting macrophage differentiation. This compound may serve as a valuable tool for investigating the role of ERK5 degradation in cancer biology and immune modulation.

Product Information

Catalog Num	A36667
Formula	C54H69N11O6S
Molecular Weight	1000.26
CAS Number	3032388-42-1
SMILES	O=C(C1=CC=CC=C1N(C)C2=NC(NC3=CC=C(C=C3OC)N4CCN(CC4)CCCCCCC(N[C@@H](C(C)(C)C)C(N5C[C@@H](C[C@H]5C(N[C@H](C6=CC=C(C=C6)C7=C(N=CS7)C)C)=O)O)=O)=O)=NC=C28)N8C

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