Fig. 1 · Structure
Documents & Downloads
PQ-1 succinate
Gap Junction Inhibitor
PQ-1 succinate is a potent gap junction inhibitor that effectively reduces dye transfer activity in retinal neurosensory R28 cells. This compound is also shown to inhibit CoCl2-induced ischemic apoptosis in retinal cells, making it a valuable tool for research into gap junction-mediated pathways and potential treatments for ischemic retinal injury. Its applications extend to studying cellular communication and neuroprotection in various models of retinal dysfunction.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 955995-51-4 |
| Applications | Gap Junction Inhibitor |
| Formula | C25H28F3N3O6 |
| Molecular Weight | 523.50 |
| SMILES | NCCCNC1=C2N=CC=C(C2=C(C(OC)=C1)OC3=CC=CC(C(F)(F)F)=C3)C.O=C(CCC(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.