PQQ-trimethylester (PQQ-TME) is a trimethylester derivative of pyrroloquinoline quinone (PQQ) that acts as a protein aggregation inhibitor. It exhibits enhanced blood-brain barrier permeability compared to its parent compound, PQQ. PQQ-trimethylester effectively inhibits the fibrillation of α-synuclein, amyloid β1-42 (Aβ1-42), and prion proteins, making it a valuable tool for research into neurodegenerative diseases.
PQQ-trimethylester (PQQ-TME) is a trimethylester derivative of pyrroloquinoline quinone (PQQ) that acts as a protein aggregation inhibitor. It exhibits enhanced blood-brain barrier permeability compared to its parent compound, PQQ. PQQ-trimethylester effectively inhibits the fibrillation of α-synuclein, amyloid β1-42 (Aβ1-42), and prion proteins, making it a valuable tool for research into neurodegenerative diseases.
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