Pralidoxime chloride

Catalog No.: A16673
AChE Reactivator
Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE), targeting AChE inhibited by organophosphate agents. It operates through a direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent, facilitating the restoration of AChE activity. Pralidoxime chloride is primarily utilized as an antidote for organophosphate poisoning, making it a critical reagent in toxicological research and therapeutic applications.
Grouped product items
Size Price Stock Qty
100mg
$25.00
In stock
500mg
$50.00
In stock
1g
$75.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE), targeting AChE inhibited by organophosphate agents. It operates through a direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent, facilitating the restoration of AChE activity. Pralidoxime chloride is primarily utilized as an antidote for organophosphate poisoning, making it a critical reagent in toxicological research and therapeutic applications.
Product Information
Catalog NumA16673
FormulaC7H9ClN2O
Molecular Weight172.61
CAS Number51-15-0
SMILESC[N+]1=CC=CC=C1/C=N/O.[Cl-]
Synonyms2-PAM chloride
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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