Pralidoxime methanesulfonate

Catalog No.: A78788
AChE Reactivator
Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE) that functions through direct nucleophilic attack by the oxime moiety on the phosphorus center of organophosphate-bound AChE. This reagent effectively restores AChE activity inhibited by nerve agents, making it critical in therapeutic interventions for organophosphate poisoning. Its primary applications include research into nerve agent effects and developing antidotes for chemical warfare agents.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE) that functions through direct nucleophilic attack by the oxime moiety on the phosphorus center of organophosphate-bound AChE. This reagent effectively restores AChE activity inhibited by nerve agents, making it critical in therapeutic interventions for organophosphate poisoning. Its primary applications include research into nerve agent effects and developing antidotes for chemical warfare agents.
Product Information
Catalog NumA78788
FormulaC8H12N2O4S
Molecular Weight232.26
CAS Number154-97-2
SMILESO=S([O-])(C)=O.O/N=C/C1=[N+](C)C=CC=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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