Fig. 1 · Structure
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Pralidoxime
AChE Reactivator
Pralidoxime is a potent reactivator of acetylcholinesterase (AChE), targeting the recovery of enzyme activity inhibited by nerve agents. It functions through a direct nucleophilic attack by its oxime moiety on the phosphorus atom of the bound inhibitor, effectively reversing the effects of organophosphate poisoning. Pralidoxime is utilized in various research applications focused on neurotoxicology and antidote development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6735-59-7 |
| Applications | AChE Reactivator |
| Formula | C7H9N2O+ |
| Molecular Weight | 137.16 |
| SMILES | C[N+]1=CC=CC=C1/C=N/O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.