Fig. 1 · Structure
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Pramipexole
Dopamine Receptor Agonist
Pramipexole is a selective dopamine D2-type receptor agonist that effectively penetrates the blood-brain barrier. It exhibits high affinity with Kis of 2.2 nM for the D2-type receptor, 3.9 nM for D2, 0.5 nM for D3, and 1.3 nM for D4 receptors. This compound is utilized in research related to Parkinson's disease and restless legs syndrome, supporting studies aimed at understanding and treating these neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 104632-26-0 |
| Applications | Dopamine Receptor Agonist |
| Formula | C10H17N3S |
| Molecular Weight | 211.33 |
| SMILES | NC1=NC(CC[C@H](NCCC)C2)=C2S1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.