Fig. 1 · Structure
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Pregnanediol
Progesterone Metabolite
Pregnanediol is a metabolite of progesterone with a specific role in modulating glucuronidation activity associated with the G71R variant of UGT1A1. It has been found to inhibit the glucuronidation process in affected individuals, contributing to breast milk jaundice. This compound is instrumental in studies exploring the biochemical pathways of progesterone metabolism and its implications in neonatal hyperbilirubinemia. Pregnanediol serves as a valuable reagent for investigating metabolic variances in human physiology and drug metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 80-92-2 |
| Applications | Progesterone Metabolite |
| Formula | C21H36O2 |
| Molecular Weight | 320.51 |
| Synonyms | NSC 1612; NSC 47462 |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@H](O)CC2)([H])[C@@]4([H])[C@@](C)([C@]([C@@H](O)C)([H])CC4)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.