Biological Activity
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.61 mL | 118.06 mL | 236.12 mL |
0.5 mM | 4.72 mL | 23.61 mL | 47.22 mL |
1 mM | 2.36 mL | 11.81 mL | 23.61 mL |
5 mM | 0.47 mL | 2.36 mL | 4.72 mL |
*The above data is based on the productmolecular weight 423.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21501 |
---|---|
Actions | Inhibitor |
CAS No. | 192329-42-3 |
Formula | C18H21N3O5S2 |
M. Wt | 423.51 |
Purity | >98% |
Synonyms | AG3340, AG 3340,AG-3340; KB-R9896, KBR9896, KB R9896 |
SMILES | O=C([[email protected]@H]1N(S(=O)(C2=CC=C(OC3=CC=NC=C3)C=C2)=O)CCSC1(C)C)NO |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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