PRMT5-IN-48 is a potent inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibiting an IC50 of 20.7 nM. This compound effectively inhibits the growth of various cancer cell lines while inducing apoptosis and causing cell cycle arrest at the G0/G1 phase. PRMT5-IN-48 is valuable for research focused on non-Hodgkin lymphoma and other malignancies associated with PRMT5 dysregulation.
PRMT5-IN-48 is a potent inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibiting an IC50 of 20.7 nM. This compound effectively inhibits the growth of various cancer cell lines while inducing apoptosis and causing cell cycle arrest at the G0/G1 phase. PRMT5-IN-48 is valuable for research focused on non-Hodgkin lymphoma and other malignancies associated with PRMT5 dysregulation.
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