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(R)-BAY-6035

Catalog No.: A26626
Histone Methyltransferase Inhibitor
(R)-BAY-6035 is a selective inhibitor of histone methyltransferase, specifically targeting the methylation of MAP3K2 by SMYD3. This compound exhibits nanomolar potency and offers high specificity against various kinases and protein lysine methyltransferases. It is suitable for research applications exploring gene regulation, epigenetic modifications, and signaling pathways related to cancer and other diseases.
(R)-BAY-6035 2283389-29-5 Histone Methyltransferase Inhibitor
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R)-BAY-6035 is a selective inhibitor of histone methyltransferase, specifically targeting the methylation of MAP3K2 by SMYD3. This compound exhibits nanomolar potency and offers high specificity against various kinases and protein lysine methyltransferases. It is suitable for research applications exploring gene regulation, epigenetic modifications, and signaling pathways related to cancer and other diseases.
Product Information
Catalog NumA26626
FormulaC22H28N4O3
Molecular Weight396.48
CAS Number2283389-29-5
SMILESO=C1C[C@@H](C)N(C(N2CC(C3)C3C2)=O)C4=CC=C(C(NCCC5CC5)=O)C=C4N1
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Epigenetics > Histone Methyltransferase